Sincerely sorry for the inconvenience.
The latest version of Glary Utilities used a new digital certificate for signing, so it needs to re-accumulate the SmartScreen reputation value . When the download or installation is locked, please choose to keep or run the program first. After a period of time, the accumulated reputation value will reach to a certain amount. Then SmartScreen will allow custom downloads and installations.
It will run normally in the near future.